A Pink round-shaped tablet with a score line on both sides, allowing it to be split into two equal parts. It is an anthelmintic containing as active substances a tetrahydropyrimidine derivative: pyrantel (as pyrantel embonate), a pro-benzimidazole derivative: febantel, and a pyrazinoisoquinoline derivative: praziquantel. It is effective against nematodes and cestodes. Praziquantel severely damages the tegument, thus disrupting the parasite’s metabolism and causing its death. Pyrantel acts as a cholinergic agonist.
It causes spastic paralysis of nematodes by blocking their neuromuscular function at the motor plate. Febantel has an inhibitory action on the polymerization of tubulin into microtubules. The resulting structural and functional metabolic disorders deplete the parasite’s energy reserves, killing it within 2-3 days.
INDICATIONS
Target Species: Dogs and Cats.
For treatment of the following nematodes and cestodes.
- Roundworms:- Ascarids (mature and immature adults): Toxocara canis, Toxascaris leonina-
- Hookworms (adults): Uncinaria stenocephala, Ancylostoma caninum-
- Whipworms (adults): Trichuris vulpis.
- Tapeworms (mature and immature adults):- Echinococcus granulosus, Echinococcus multilocularis, Dipylidium caninum, Taenia spp.
DOSAGE AND ADMINISTRATION ROUTE
For oral administration only.
Dosage:
For the treatment of dogs, 1 tablet per 10 kg of body weight (15 mg of febantel, 5 mg of pyrantel (equivalent to 14.4 mg of pyrantel embonate), and 5 mg of praziquantel per kg), i.e.
